Ion AmpliSeq™ Inherited Cancer Research Panel  Hide Panel Description

Research to identify specific genetic causes of inherited cancers is important but can be difficult because of pleiotropy, locus heterogeneity and accessibility of information. The Ion AmpliSeq™ Inherited Cancer Research Panel was designed based on extensive curation of peer-reviewed literature, disease research databases and consultation with key opinion leaders.

Number of amplicons 3,340 Average Amplicon Length 242 bp Insert Size 192 bp
Recommended Application Germline mutation detection Compatible PlatformsIon S5™ System, Ion PGM™ System, Ion Proton™ System Sample Type Standard
Design Statistics Number of genes in panel: 134
Average gene coverage: 99.7%
Observed Performance Uniformity of amplicon coverage: 94.6%
% reads on target: 96%
Input DNA required 10 ng per pool
20 ng total (2 pools)
Disease Research Area: Inherited Cancers
  • Chip Calculator
  • 2 (20 ng)
  • Pools (Input DNA) Multiple Pools
  • Pool1: 1676 amplicons | Pool2: 1664 amplicons
  • 372.45 kb
  • Panel Size