Ion AmpliSeq™ Deafness Research Panel v2  Hide Panel Description

Research to identify specific genetic causes of hearing impairment is important but can be difficult because of pleiotropy, locus heterogeneity and accessibility of information. The Ion AmpliSeq™ Deafness Research Panel v2 was designed based on extensive curation of peer-reviewed literature, disease research databases and consultation with key opinion leaders.

Number of amplicons 3,520 Avg Amplicon Length 254 bp Insert Size 207 bp
Recommended Application Germline mutation detection Compatible PlatformsIon S5™ System, Ion PGM™ System, Ion Proton™ System Sample Type Standard
Design Statistics Number of genes in panel: 126
Average gene coverage: 99%
Observed Performance Uniformity of amplicon coverage: 94%
% reads on target: 95%
Input DNA required 10 ng per pool
20 ng total (2 pools)
Disease Research Area: Inherited Hearing Disorders
  • Chip Calculator
  • 2 (20 ng)
  • Pools (Input DNA) Multiple Pools
  • Pool1: 1770 amplicons | Pool2: 1750 amplicons
  • 380 kb
  • Panel Size